Volume 21, Issue 4 (2026)
Editorial Board
Review Articles
Effects of cleaning protocols on the material properties of clear aligners and retainers: A systematic review
Yao-Chang Chiang, Tu Manh Nguyen, Thuy-Trang Thi Ho, Loc Minh Lu, Yang-Che Wu, Tong-Hsien Chow, Chiang-Wen Lee, Fang-Yu Fan, Li-Nai Chen, and I-Ta Lee
The clinical applications of platelet-rich plasma and platelet-rich fibrin combined with photobiomodulation in regenerative dentistry: A literature review
Maryam Pourhajibagher, Rashin Bahrami, and Abbas Bahador
Herbal medicine for oral ulcer treatment: mechanisms, efficacy, and therapeutic potential
Shinn-Zong Lin, Tsung-Hsien Chuang, Chih-Yang Huang, Tsung-Jung Ho, and Yi-Pang Lee
Competency-based medical education and entrustable professional activities in dental education: global perspectives and implications for Taiwan
Johnson Hsin-Chung Cheng and Sharon Hsuan-Jung Chen
Performance of large language models in answering orthodontic questions: a scoping review
Tu Manh Nguyen, Fang-Yu Fan, Ying-Sui Sun, Yang-Che Wu, Sheng-Wei Feng, Hao-Ting Chen, I-Ta Lee, and Pao-Chang Chiang
Original Articles
The pH-PI3K/AKT/mTORC1 axis in the survival of stem cells from the apical papilla: a critical target for rescue by microenvironment-engineered hydrogels in pulp regeneration
Chunlei Zhang, Haisheng Cao, Jie Li, Changqing Yan, Yang Liu, Shuguo Zheng, and Xiaozhe Wang
International comparison of oral hypofunction among community-dwelling older adults in three Asian countries: A cross-sectional and multi-national study
Ryosuke Yanagida, Kohei Yamaguchi, Kazuharu Nakagawa, Chantaramanee Ariya, Patcharaphol Samnieng, Megan F Liu, Nai-Chia Teng, Ting-Yi Renn, Rieko Moritoyo, Sirinthip Amornsuradech, Kanako Yoshimi, and Haruka Tohara
Accuracy of full-arch implant scans using different horizontal scan bodies in an angulated model: An in vitro study
Tsung-Yu Lin, Tong-Mei Wang, and Li-Deh Lin
Development and clinical validation of an artificial intelligence–assisted radiographic system for predicting periodontal pocket severity using full-mouth radiographs.
Yi-Tai Ho, Tsui-Hsien Huang, Cheng-Han Shie, Tao-Wei Chang, Chun-Te Ho, and Chia-Tze Kao
Osteoblastogenesis stimulation by human umbilical cord stem cell secretome during maxillary expansion
Alexander Patera Nugraha, Guang Hong, Firdaus Hariri, I Gusti Aju Wahju Ardani, Adya Pramusita, Nurul Aisyah Rizky Putranti, Nindya Rizky Anjani Marhendra, Naora Dewi Rahma Fadzila, Ananda Firman Putranto, Muhammad Luthfi, Wibi Riawan, Putri Cahaya Situmorang, Rony Abdi Syahputra, Thantrira Porntaveetus, Khairul Anuar Shariff, Nissia Ananda, Maudina Dwi Heriasti, and Kotaro Tanimoto
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in 430 patients with recurrent aphthous stomatitis
Yi-Ping Wang, Yi-Pang Lee, Yu-Hsueh Wu, Julia Yu-Fong Chang, Andy Sun, and Chun-Pin Chiang
Deep learning-based automated per-tooth detection and segmentation from unretracted smile photographs
Hsuan Chen, Khoa Dang Nguyen, Hong Thi-Phuong Doan, Mu-Chen Yang, Ya-Chu Chang, Anand Marya, Guang Hong, Ding-Han Wang, and Ming-Lun Hsu
Avian mesenchymal stem cell-derived extracellular vesicle alleviates the Porphyromonas gingivalis lipopolysaccharide induced gingival fibroblast senescence
Han-Chieh Yang, Earl Fu, Yu-Tang Chin, Ju-Sheng Shieh, Wei-Ni Lin, and Cheng-Yang Chiang
Developing an automated cytology-based DNA ploidy test for detecting oral squamous cell carcinoma in Taiwan: A feasibility study
Pei Hsuan Lu, Kelly Yi Ping Liu, Julia Yu Fong Chang, Long‐Wei Lin, Hao-Hung Chang, Chen-Han Chang, Shang Hsuan Peng, and Catherine F. Poh
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in recurrent aphthous stomatitis patients with vitamin B12 deficiency
Yi-Ping Wang, Yi-Pang Lee, Yu-Hsueh Wu, Julia Yu-Fong Chang, Andy Sun, and Chun-Pin Chiang
A bibliometric evolution of molecular mechanisms and emerging research trends of therapeutic resistance in oral cancer
Chu-Yen Chien, Ying-Chen Chen, Jia-Rong Wu, Hsu-Hua Chu, Yi-Jen Hung, and Yi-Shing Shieh
Effects of low-level Er:YAG laser irradiation on endothelial angiogenic responses in diabetes: an in vitro study
Bruna Akinaga Moreira, Koji Mizutani, Natsumi Saito, Lu Chen, Shu Takemura, Keita Nakagawa, Yujin Ohsugi, Taichen Lin, Takanori Iwata, and Akira Aoki
Blood vessels expressing CD31 and endomucin contribute to the formation of new hard tissue via osterix-expressing cells during the healing process of pulp revascularization in mice
Takatoshi Ikarashi, Keisuke Mitomo, Kentaro Tashiro, Mayuka Haketa, Toshihide Mizoguchi, Akira Yamaguchi, and Takashi Muramatsu
Physico-mechanical properties and Streptococcus mutans biofilm formation of bio‑based flexible crowns versus stainless steel and zirconia crowns for pediatric full-coverage restorations
Tzu-Yu Peng, Szu-Yu Lai, Yan-An Wu, Ya-Ting Yang, Yuichi Mine, and Huei-Yu Huang
Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative recurrent aphthous stomatitis patients
Yu-Hsueh Wu, Yi-Ping Wang, Yi-Pang Lee, Julia Yu-Fong Chang, Andy Sun, and Chun-Pin Chiang
Adhesion performance of conventional and high-translucency zirconia: effects of airborne-particle abrasion and 10-methacryloyloxydecyl dihydrogen phosphate treatments
Chia-Ling Li, Li-Li Kang, Jui-Che Lin, and Shu-Fen Chuang
Current orthognathic surgery practices in Taiwan: A questionnaire survey among board-certified oral and maxillofacial surgeons
Chia-Wei Nien, Bo-Jun Chen, Ryoji Yoshida, Yoichi Ohiro, and Chih-Yuan Fang
Sesamin suppresses high glucose-induced cyclooxygenase-2 and prostaglandin E2 production through Toll-like receptor 2-dependent oxidative stress in human gingival fibroblasts
Ya-Lun Li, Yu-Chia Hsu, Fang-Yu Fan, Yung-Li Wang, Yang-Che Wu, Sin-Yu Li, Thi Thuy Tien Vo, Yu-Chia Chang, Yin-Tzer Shih, and I-Ta Lee
Interaction between removable partial denture use and number of natural teeth on health-related quality of life in older adults: A cross-sectional study
Pai-Shien Liao, Chia-Hsuan Chou, Ya-Xin Zheng, Jiiang-Huei Jeng, Wan-Chuen Liao, and Ying-Fang Chen
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in recurrent aphthous stomatitis patients with iron deficiency
Yi-Ping Wang, Yu-Hsueh Wu, Yi-Pang Lee, Julia Yu-Fong Chang, Andy Sun, and Chun-Pin Chiang
Universal coverage but unequal access: an area-level statistical and policy analysis of Taiwan’s dental workforce
Chien-Yang Yeh, Shih-Hsien Yang, Wei-Chia Su, Hsin-Hu Chen, Wei-Chin Hsu, and Su-Feng Chen
Routine dental scaling and reduced risk of serious infections in individuals with moderate-to-severe cerebral palsy: A nationwide population-based cohort study
Li-Wei Ou-Yang, Yu-Tung Huang, Ya-Ting Chang, Hsin-Mao Hsu, Shih-Hao Chang, Chia-Ling Wu, and Tsung-Chieh Yao
Artificial intelligence assisted multitask framework for dental detection and root canal filling assessment on periapical radiographs
Chia-Lin Hsu, Li Wei Ou-Yang, Chih-Hao Chang, Yuan-Jin Lin, Po-Lin Huang, Kai-Syun Chiu, Heng-Chia Chen, Tsung-Yi Chen, Jia-Ching Wang, Wei-Chen Tu, and Patricia Angela R. Abu
Optimizing Light-curing Protocols for Clear Aligner Attachments: A Comparison of Bulk-fill and Conventional Resin Composites
Narudol Treethanya, Nuntinee Nanthavanich Saengfai, Choltacha Harnirattisai, Pongstorn Putongkam, Chia-Tze Kao, and Peerapong Santiwong
The bridge to practice: A regulatory analysis of pre-licensure dental training in Taiwan
Wei-Chia Su, Hsin-Hu Chen, Ching-Yu Yen, Hsun-Yu Liu, Yuan-Der Huang, and Jian-Hong Yu
Active learning-assisted deep learning for automated maxillary sinus segmentation in dental cone-beam computed tomography
Hsuan Chen, Khoa Dang Nguyen, Chih-Ling Chang, Hong Thi-Phuong Doan, Ya-Chu Chang, Thantrira Porntaveetus, Guang Hong, Wen-Liang Lo, Ding-Han Wang, and Ming-Lun Hsu
Do anatomy, physiology and biochemistry subject scores predict future academic performance? A longitudinal analysis of undergraduate dental students across all professional years.
Shahid Akhtar Akhund and Hassan Shaibah
Deer antler tip cell culture supernatant restores endothelial barrier function and angiotensin converting enzyme 2/endothelial nitric oxide synthase nitric oxide signaling impaired by Porphyromonas gingivalis lipopolysaccharide
Ming-Shou Hsieh, Ya-Ting Yang, Chin-Sheng Huang, Ting-Yi Renn, Chuen-Kai Wang, Chia-Chen Hsu, Wei Jen Chang, and Yu-Sheng Chang
Hollow fiber assay microtube array membrane (MTAM-HFA) for personalized anticancer drug screening in selection of concurrent chemoradiotherapy in oral squamous cell carcinoma
Shan-Ju Chou, Po-Chih Hsu, Chee Ho Chew, Wan-Ting Huang, Amanda Lin Chen, Chen-Yin Yong, Chia-Che Wu, Chia-Lun Chang, Chien-Chung Chen, and Kuan-Chou Lin
Heat shock factor 1 promotes cell migration and predicts poor prognosis in oral squamous cell carcinoma
Fang-Yu Wu, Hui-Hsin Ko, Wen-Ren Lin, and Shih-Jung Cheng
Surgical treatment of osteoradionecrosis of the jaw following radiotherapy for oropharyngeal cancer: A retrospective clinical analysis in a single-center
Yu Nakai, Ken-ichiro Sakata, Kazuhito Yoshikawa, Taku Maeda, Tougo Tanabe, Masayuki Shinohara, Kenji Imamachi, Hiroshi Hikasa, Jun Sato, and Ikuya Miyamoto
Runt-related transcription factor 2 transcriptionally represses Sirtuin 1 to regulate osteoclastogenesis and tooth eruption
Jie Li, Changqing Yan, Xinyi Sun, Chenying Zhang, Xiaozhe Wang, Yang Liu, and Shuguo Zheng
Evaluation of retrieval-augmented generation (RAG) with GPT-4o for maxillofacial prosthodontics clinical questions
Vinsensia Launardo, Merve Koseoglu, Lucky Susanto, Michael Kase, Amanda Colebeck, Heidi Huber, Maribeth Krzesinski, Derry Wijaya, Muhammad Ruslin, Alvin Gerard Wee, Heng-Li Huang, Lih-Jyh Fuh, and Cortino Sukotjo
Prediction of adequate alveolar ridge contours for dental implant placement using an artificial intelligence-based algorithm
Hao-Chieh Chang, Shan-Pin Pan, Cheng-Liang Wu, Wei-Chan Hsu, Yi-Chun Weng, and Po-Chun Chang
Biological performance enhancement of Ni-free Zr-based bulk metallic glass for dental implants via nitrogen plasma immersion ion implantation
Hsun-Miao Huang, Ying-Sui Sun, Ya-Lin Huang, Kai-Yi Lin, Thantrira Porntaveetus, Thanaphum Osathanon, Wei-Cheng Chen, and Her-Hsiung Huang
Prognostic impact of the preoperative Naples prognostic score on overall and progression-free survival in surgically treated oral squamous cell carcinoma: a retrospective cohort study from a Taiwanese medical center
Pei-Lun Hsueh, Yu-Hsuan Li, Cheng-Yu Yang, Gu-Jiun Lin, Yuan-Wu Chen, and Wei-Chin Chang
Correlation between preoperative mandibular restriction and functional outcomes after arthroscopic discopexy for temporomandibular joint internal derangement
Yen-Hung Lin Arthur, Chih-Hua Yeh, Ying-An Chen, and Hui-Hsin Ko
Effects of 850-nm light-emitting diode photobiomodulation on pain intensity and dentin sialoprotein levels during canine distalization: a randomized controlled trial.
Thanh Thuy-Nhat Cao, Anh Ho-Quynh Nguyen, Hung Trong Hoang, Tham Dong Khac, Phuc Hoai Le, Tu Trinh HK, Kieu-Minh Le, and Diem Truong
Significantly higher frequencies of anemia, vitamin B12 deficiency, and hyperhomocysteinemia in recurrent aphthous stomatitis patients with macrocytosis
Yu-Hsueh Wu, Yi-Ping Wang, Yi-Pang Lee, Julia Yu-Fong Chang, Andy Sun, and Chun-Pin Chiang
Changes of RNA expression in aging periodontal ligament cells
Su Kang Kim, Ju Ri Ye, Gyutae Kim, Ju Yeon Ban, and Sang Wook Kang
The association between dental prophylaxis and diabetes outcomes: a 15-year cohort study
Hsueh-Fen Chen, Shih-Feng Weng, Ju-Hui Wu, Mei-Yueh Lee, Hui-Min Hsieh, Yu-Ting Huang, and Yi-Cai Liu
Formulation modification of silver diamine fluoride to improve clinical handling and dentin tubule occlusion
Liangyu Chang, Yutzu Wu, Powen Lu, Iwen Chen, Weifang Lee, Chunche Lin, Renjei Chung, Poonam Negi, Naichia Teng, and Jenchang Yang
An artificial intelligence assisted framework for automated quantified root canal curvature measurement on periapical radiographs
Ming-Yi Chen, Shih-Lun Chen, Yu-Jen Chang, Yuan-Jin Lin, Chiung-An Chen, Tsung-Yi Chen, Kuo-Chen Li, Wei-Chen Tu, and Patricia Angela R. Abu
Exosomes derived from bone substitute-induced gingival mesenchymal stem cells promote angiogenesis
Chongyu Shen, Zheng Guan, Rui Chu, Zhengyin Li, Jiangting Lu, and Liangkun Xie
Submicron diamond-assisted irrigation enhances apical biofilm removal under sonic and ultrasonic activation: An ex vivo study
Yung-Szu Hsu, Nai-Chia Teng, Sin-Yu Chen, Huan-Cheng Chang, Haw-Ming Huang, and Sung-Chih Hsieh
Silencing the miR-132/SIRT1 Axis Suppresses NLRP3 Inflammasome Activation and Myofibroblast Differentiation in Oral Submucous Fibrosis
Ming-Yung Chou, Min Yee Ng, Yi-Wen Liao, Chuan-Hang Yu, Cheng-Chia Yu, and Sin-Jia Tseng
Biphasic remodeling and trabecular-cortical uncoupling in the jawbone during antiresorptive therapy and medication-related osteonecrosis: a quantitative imaging analysis
Ling-Ying Wei, Jun-Ching Lee, Ching-Ming Chiu, Sang-Heng Kok, Hung-Ying Lin, Wei-Yih Chiu, Hao-Hueng Chang, Shih-Jung Cheng, and Jang-Jaer Lee
Artificial intelligence in dentistry: A cross-domain bibliometric analysis of technologies, functional applications, and dental specialties
YingHui Yang, Cheng-Chia Yu, and Min Yee Ng
Keratin 18 as a cytoskeletal regulator of epithelial–mesenchymal plasticity and prognostic risk in oral squamous cell carcinoma
Tuan-Yu Kao, Hsuan-Chao Lin, Chien-Wei Lai, Julia Yu-Fong Chang, Feng-Chiao Tsai, Jang-Jaer Lee, and Jean-San Chia
Anemia, hematinic deficiencies, and gastric parietal cell antibody positivity in recurrent aphthous stomatitis patients with or without hyperhomocysteinemia
Yi-Ping Wang, Yu-Hsueh Wu, Yi-Pang Lee, Julia Yu-Fong Chang, Andy Sun, and Chun-Pin Chiang
Short Communications
A scientometric study on research trends and characteristics of Kimura disease
Zhongjing Lv, Yiming Luo, Wei Liu, and Jian Yuan
Very early interceptive management of class III malocclusion in primary dentition using a prefabricated functional education appliance: Preliminary clinical observations
Thi Ngoc Anh Do, Thi Huong Le, I-Ta Lee, Tong-Hsien Chow, Pao-Chang Chiang, and Thi Thuy Tien Vo
A scientometric study on research trends and characteristics of lymph node metastasis in oral cancer
Linjian Huang, Xiaocui Tong, Wei Liu, and Xinyu Zhang
Perspective
Oral health knowledge across cultural boundaries: A Physiology and Hygiene Textbook from the Tamsui Middle School during the Japanese colonial period
Hung-Lun Pan, Feng-Chou Cheng, and Chun-Pin Chiang
Correspondences
Application of medical imaging examinations for temporomandibular disorders under Taiwan's National Health Insurance system
Feng-Chou Cheng, Mu-Hsiung Chen, Yu-Ling Wu, and Chun-Pin Chiang
Light-curing staining materials and application techniques for dental resin restorations
Fu-Chuan Tsai, Kuo‑Ning Ho, Yu-Chieh Lin, and Wei-Chun Lin
Topical fluoride treatment for irradiated head and neck cancer patients under Taiwan's National Health Insurance system
Feng-Chou Cheng, Mu-Hsiung Chen, Sheau-Jing Yu, and Chun-Pin Chiang
The evolution of artificial intelligence and deep learning in removable partial denture design
Fu-Chuan Tsai, Hsin-Hua Chou, Takashi Saito, and Wei-Chun Lin
The clinical potential of cone-beam computed tomography image segmentation in dentistry
Hsin-Hua Chou, Takashi Saito, Chih-Kai Huang, and Wei-Chun Lin
Digital impression workflows and mucosal considerations in removable complete dentures
Fu-Chuan Tsai, Hsin-Hua Chou, Takashi Saito, and Wei-Chun Lin
Virtual patient technology enabled the reconstruction of craniofacial hard and soft tissues through the integration and superimposition of multimodal dental imaging datasets
Hsin-Hua Chou, Kuo‑Ning Ho, Takashi Saito, and Wei-Chun Lin
Roles and functions of the dental division at the National Taiwan University Cancer Center
Feng-Chou Cheng, Yu-Jie Shen, Shu-Yu Liu, and Chun-Pin Chiang
Exploring exhibited works on dentistry-related topics at the Student Science Fair Projects in Taiwan from 1970 to 2025
Mei-Huei Li, Feng-Chou Cheng, Kun-Ming Lien, and Chun-Pin Chiang
Ruptured silicone cheek implant mimicking odontogenic infection: A diagnostic pitfall
Kimiko Ohgi, Tomoko Shiraishi, Toyohiro Kagawa, and Yasunori Yoshinaga
Radiographic signs of numb chin syndrome as an initial indicator of Burkitt lymphoma: A case report
Yu-Hsiang Tang, Meng-Ling Chiang, and Jyh-Kwei Chen
Maxillary furcation-involved Class II subclass B molar with advanced distal vertical bone defect treated by Er:YAG laser-assisted comprehensive periodontal pocket therapy under a microscope: A case report
Taichen Lin, Yoichi Taniguchi, Koji Mizutani, and Akira Aoki
Recurrent maxillary medication-related osteonecrosis of the jaw with maxillary sinusitis in an edentulous patient: a possible bidirectional relationship
Wun-Ting Lin, Yu-Nung Lee, Yu-Fen Yen, and Ken-Chung Chen
Comment on “Zygomatic fracture characteristics and their association with brain injury: Evidences from a 10-year retrospective study in northern Taiwan”
Yang-Zhou Huang, Kun Zhao, Jing Xiao, and Zhou-Hui Wu
Corrigendum
