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Volume 20, Issue 4 (2025)

Review Articles

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Bidirectional association between obesity and chronic periodontitis: Inflammatory pathways and clinical implications
Yu-Chao Chang, Tsung-Po Chen, Hui-Chieh Yu, and Wen-Yuan Lin

                  pp. 2021 - 2025

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Accelerated senescence animal models and application in dentistry: A scoping review
siwei wang, Jiayu Mou, Jiarui Jiang, Qi He, Mulan Qahar, Daniele De Santis, Fang Qi, Guangchao Xu, and Jianguo Liu

                  pp. 2026 - 2038

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The potential effect of photobiomodulation on oral mucositis induced by head and neck radio-chemotherapy: A literature review
Rashin Bahrami, Shahriar Eftekharian, Raha Jafarieh, Maryam Pourhajibagher, and Abbas Bahador

                  pp. 2039 - 2045

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Unveiling the characteristics and surface modification of titanium, zirconia, and polyetheretherketone dental implants
Shinn-Jyh Ding, Yu-Hsuan Cheng, and Chun-Cheng Chen

                  pp. 2046 - 2057

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Boosting the antibacterial potency of antimicrobial photodynamic therapy against oral pathogens through supplement agents: A narrative review
Rashin Bahrami, Maryam Pourhajibagher, Ehsan Kazemi Moghaddam, and Abbas Bahador

                  pp. 2058 - 2065

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Roles of basic fibroblast growth factor, stem cells from dental pulp and apical papilla in the repair and regeneration of dental pulp and other tissues/organs
Jiiang-Huei Jeng, Pin-Hsuan Wu, Yan-Hsiung Wang, Ying-Chu Lin, Ya-Shuan Chou, and Mei-Chi Chang

                  pp. 2066 - 2075

Original Articles

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LncRNA LINC00704 drives cancer stemness and malignant properties in oral squamous cell carcinomas by sponging miR-204
Pei-Yin Chen, Lo-Lin Tsai, Shih-Min Wang, Yi-Wen Liao, Cheng-Chia Yu, and Shih-Chi Chao

                  pp. 2451 - 2459

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Analyzing the performance of multimodal large language models on visually-based questions in the Japanese National Examination for Dental Technicians
Yuichi Mine, Tsuyoshi Taji, Shota Okazaki, Saori Takeda, Tzu-Yu Peng, Saiji Shimoe, Masato Kaku, Hiroki Nikawa, Naoya Kakimoto, and Takeshi Murayama

                  pp. 2460 - 2466

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In vitro evaluation of novel composite bioceramic filaments for alveolar bone regeneration
Hao-Hueng Chang, Yu-Ting Li, Ju-Hsuan Yang, Yu-Hsin Chang, and Chun-Pin Lin

                  pp. 2084 - 2091

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Histological insights into the nasal superficial musculoaponeurotic system implicating to oral and maxillofacial surgery – A preliminary study from cadavers
I-Ta Lee, Nguyen Anh Tuan Ho, Dang Khoa Tran, Dang Dieu Pham, Thanh Van Nguyen, Yang-Che Wu, and Chien-Fu Tseng

                  pp. 2098 - 2103

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Artificial intelligence-assisted enhancement of diagnostic accuracy and efficiency in detecting cervical lymph node metastases in oral squamous cell carcinoma
Chih-Huang Tseng, Chang-Wei Su, Yu-Min Lin, Yu-Hsun Kao, Wei-Cheng Lin, Hao-Tang Wang, Ching-Yi Chen, Wen-Chen Wang, and Yuk-Kwan Chen

                  pp. 2092 - 2097

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Oral soft tissue diagnosis as a novel teledentistry framework for the post-pandemic era: A systematic review
Chung-Ming Liu, Israyani Israyani, Christine Rovani, Su-Feng Chen, Khanisyah Gumilar, Shang-Ming Wang, and Jian-Hong Yu

                  pp. 2104 - 2117

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Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative oral lichen planus patients
Chung-Pin Chiang, Yu-Hsueh Wu, Julia Chang, Yi-Pang Lee, Yi-Ping Wang, and Andy Sun

                  pp. 2118 - 2126

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Flammulina velutipes polysaccharides exhibit potent antioxidant and anti-pyroptotic properties in diabetes-associated periodontitis: A preliminary in vitro study
Chun-Cheng Chen, Ni-Yu Su, Szu-Han Chen, Yi-Wen Liao, Chang-Wei Hsieh, and Cheng-Chia Yu

                  pp. 2127 - 2134

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Accuracy and fitness of digital light processing-fabricated resin-based permanent crowns after thermal aging
Wei-Fang Lee, Pei-Wen Peng, Wei-Jen Chang, Jia-Syuan Chou, Le-Xin Chen, Cheng-Cho Chuang, Yi-Jie Lu, and Min-Chieh Hsieh

                  pp. 2135 - 2142

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Effects of horizontal dimensional malocclusion on changes in smile measurements in frontal, oblique, and lateral views
Johnson Hsin-Chung Cheng, Ming-Han Feng, Ching-Cheng Hsu, and Ardiansyah Pawinru

                  pp. 2143 - 2153

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The mesial–mesial/distal–distal (MM-DD) occlusal adjustment technique: A 2–21.5-year retrospective study on preventing open contacts in posterior implant restorations
Chiun-Lin Steven Liu, Shih-Cheng Wen, Ching-Jung Chang Chien, and Je-Kang Du

                  pp. 2163 - 2175

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Human umbilical cord mesenchymal stem cells secretome and nanoemulsion propolis combination ameliorate osteoclastogenesis in lipopolysaccharide-induced osteolysis in hyperglycemia rats
Alexander Patera Nugraha, Kunhua Yang, Adya Pramusita, Nurul Aisyah Rizki Putranti, Muhammad Luthfi, Nastiti Faradillah Ramadhani, Ratri Maya Sitalaksmi, Putri Cahaya Situmorang, Muh Artasasta, Ananto Ali Alhasyimi, Wibi Riawan, Albertus Putera Nugraha, Khairul Anuar Shariff, Kotaro Tanimoto, and Guang Hong

                  pp. 2181 - 2188

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Impact of orthodontic education on the perception of attractiveness and acceptance of facial profiles in adult Taiwanese and Caucasian women
Yu-Chuan Tseng, Shih-Chieh Chen, Szu-Ting Chou, Shih-Hsuan Lin, Chao-Yu Lu, Wan-Yi Zhao, and Chun-Ming Chen

                  pp. 2195 - 2203

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Impact of scan body splinting on the accuracy of complete-arch digital implant impressions
Ilser Turkyilmaz

                  pp. 2189 - 2194

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Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in oral lichen planus patients with macrocytosis
Chung-Pin Chiang, Julia Yu-Fong Chang, Yu-Hsueh Wu, Yi-Pang Lee, Yi-Ping Wang, and Andy Sun

                  pp. 2204 - 2210

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Innovative 3D-printed dental teaching model for root canal treatment simulation
Szu-Yu Chen, Yu-Chiao Wu, Jia-Rong Wu, Che-Yi Lin, Yi-Jen Hung, Tsai-Wang Huang, and Yi-Shing Shieh

                  pp. 2211 - 2218

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Effects of varying anteroposterior craniodentofacial morphologies on three-dimensional smile variables
Hsin-Chung Cheng and Patcharamas Banditsaowapak

                  pp. 2219 - 2230

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miR-376a/Neuropilin-1 axis mediates the cancer stemness in oral squamous cell carcinoma-an in vitro study
Yu-Chao Chang, Yi-Wen Liao, Cheng-Chia Yu, and Heng-Yi Liao

                  pp. 2238 - 2244

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Evaluating the impact of varying post angulations on the fracture resistance of maxillary incisors restored with polyethylene fiber posts
Chung-Ming Liu, Christine Rovani, Nurhayaty Natsir, Irfan Yamin, Aries Trilaksana, Li-Rong Kuo, and Bai-Hung Huang

                  pp. 2231 - 2237

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Increased medications in the aged patients with burning mouth syndrome: A potentially overlooked risk factor
Yu-Hsueh Wu, Chun-Pin Chiang, and Chih-Chung Chien

                  pp. 2245 - 2249

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MicroRNA let-7a mitigates the progression of oral submucous fibrosis by targeting high-mobility group AT-hook 2
Hui-Wen Yang, Chih-Yuan Fang, Shih-Chi Chao, Yi-Wen Liao, Cheng-Chia Yu, and Yu-Wei Chiu

                  pp. 2265 - 2272

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Development of zinc partially-stabilized cement carrying growth factor and anti-inflammatory drug for vital pulp therapy
Chun-Pin Lin, Tsao-Li Chuang, Chih-Chun Chang, and Chun-Liang Yeh

                  pp. 2250 - 2257

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Evaluation of an anti-snoring device featuring a Ni–Ti alloy elastic linkage in a simulated clinical environment
Chun-Pin Lin, Ming-Sung Hsu, Tung-Lin Tsai, Shih-Jung Cheng, Yu-Sheng Lin, and Li-Wen Weng

                  pp. 2258 - 2264

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Assessing the impact of apicoectomy on autotransplantation success rates: A six-year retrospective cohort study in Taiwan
Yu-Hsueh Wu, Kai-Yun Tso, and Wei-Chih Chiu

                  pp. 2273 - 2282

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Single-cell isolation reveals 5 fluorouracil-resistant subclones in oral squamous cell carcinoma: New insights into stemness and epithelial–mesenchymal transition for targeted therapies
Wei-Chia Su, Yi-Ming Chang, Hsin-Hu Chen, Su-Feng Chen, Meng-Hua Yang, Yu-Chun Lin, and Jian-Hong Yu

                  pp. 2283 - 2291

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Evaluating the impact of orthognathic surgery on mental health, function, and quality of life
Chia Tze Kao, Chuan-Yi Kao, Tsui-Hsein Huang, Chun-Te Ho, and Yi Hsien Hsieh

                  pp. 2292 - 2300

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Performance of artificial intelligence chatbots in National dental licensing examination
Chad Chan-Chia Lin, Jui-Sheng Sun, Chin-Hao Chang, Yu-Han Chang, and Jenny Zwei-Chieng Chang

                  pp. 2307 - 2314

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The potential bactericidal effect of oral probiotics on extrinsic black stain-associated bacteria in children: An in-vitro and in-vivo study
Nour Abdelmonem Wahba, Dina Sharaf, Mohamed Bissar, Ahmed El-Motayam, and Basma Nagi

                  pp. 2315 - 2321

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Corylin attenuates oral squamous cell carcinoma progression through c-Myc inhibition
Chin-Chuan Chen, Chi-Yuan Chen, Li-Fang Chou, Chau-Ting Yeh, Yi-Tsen Liu, Yu-De Chu, Hsin-Wei Lin, Kai-Yin Chen, Cheng-Chia Yu, and Tong-Hong Wang

                  pp. 2322 - 2331

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Brain activation generated by periodontal initial treatment
Kosuke Muraoka, Masafumi Oda, Kenichi Yoshino, Tatsurou Tanaka, Masaki Morishita, Taiji Nakamura, Shino Yamaguchi, Kazuo Sonoki, Yasuhiro Morimoto, Keisuke Nakashima, and Shuji Awano

                  pp. 2348 - 2352

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A novel buccal bone augmentation technique around non-contained and exposed implant threads: Clinical, histologic and histomorphometric evaluations on the treatment outcome
David M Kim, Myron Nevins, Stefano Parma-Benfenati, Primo Gelletti, Chia-Yu Chen, Miruna Maracine, Traian Comanescu, and Wei-Jen Chang

                  pp. 2332 - 2338

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Beyond dental radiographs, a radiomics-based study for the classification of caries extension and depth
Gianrico Spagnuolo, Niccolò Giuseppe Armogida, Francesca Angelone, Parisa Soltani, Luigi Esposito, Mario Sansone, Sandro Rengo, Francesco Amato, Carlo Rengo, and Alfonso Maria Ponsiglione

                  pp. 2353 - 2362

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Influence of the coronavirus pandemic on domiciliary dental care and associated problems in Japan -a questionnaire study
Yoshiyuki Hagiwara, Hiroyasu Yasuda, Keisuke Seki, Daisuke Akita, Kenji Ito, and Tetsuo Ohyama

                  pp. 2375 - 2380

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Serotonin promotes lip sensory recovery after inferior alveolar nerve transection via histone serotonylation
Li Ye, Suning Mao, Gaowei Zhang, Zhongkai Ma, Pingchuan Ma, and Chunjie Li

                  pp. 2363 - 2374

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Lunar life drives jawbone formation
Kotaro Sato, Naoka Kouyama, Shinya Akatsuka, Yashiro Motooka, Qinhong Wang, Hideharu Hibi, and Shinya Toyokuni

                  pp. 2399 - 2406

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Association between dental scaling and the lower risk of oral cancer: A population-based nested case-control study
Yu-Chao Chang, Ying-Ting Yeh, Chiao-Wen Lin, Ping-Ju Chen, Chia-Yi Lee, Yu-Hsun Wang, Shun-Fa Yang, and Chao-Bin Yeh

                  pp. 2392 - 2398

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Propofol-induced osteogenic differentiation in dental pulp stem cells: Modulation of MAPK signaling under inflammatory conditions
Eun-Jung Kim, Mi Kyoung Kim, Giyoung Yun, Cheul-Hong Kim, Ji-Young Yoon, Hee Young Kim, and Hyae Jin Kim

                  pp. 2416 - 2426

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Recombinant human fibroblast growth factor-2 promotes surgical-wound healing in the rat gingiva
Yasunori Yoshinaga, Naoki Maruo, Kimiko Ohgi, Hiroaki Yamato, Nanako Tsuchimochi, Masanobu Nakagami, and Ryuji Sakagami

                  pp. 2407 - 2415

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Benchmarking multimodal large language models on the dental licensing examination: Challenges with clinical image interpretation
Yuichi Mine, Shota Okazaki, Tsuyoshi Taji, Hiroyuki Kawaguchi, Naoya Kakimoto, and Takeshi Murayama

                  pp. 2427 - 2435

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Evaluating communication and clinical skills in objective structured clinical examination (OSCE) using a low-cost neck-mounted device, insights from a first-person perspective
Chao-An Chen, Yu Ching Liu, I-Ching Liao, Ching-Yi Wu, Chung-Han Ho, Chih-Hao Lu, and Kuan-Liang Chen

                  pp. 2436 - 2442

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γ-Mangostin mitigates impaired wound healing and pyroptosis in human gingival fibroblasts induced by advanced glycation end products
Chao-Yen Huang, Pei-Yin Chen, Min Yee Ng, Yi-Wen Liao, Cheng-Chia Yu, and Szu-Han Chen

                  pp. 2443 - 2450

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Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with normocytosis
Chun-Pin Chiang, Julia Yu-Fong Chang, Yu-Hsueh Wu, Yi-Pang Lee, Yi-Ping Wang, and Andy Sun

                  pp. 2076 - 2083

Short Communications

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Evaluating the diagnostic value and prospects of genomic and mutational sequencing in malignant transformation of oral leukoplakia
Wei Liu, Jian Yuan, Yuhan Zhu, Zirui Wang, and Zhongjing Lv

                  pp. 2472 - 2478

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Carbon dioxide laser-assisted bone regenerative therapy without membrane use
Yoichi Taniguchi, Akira Aoki, Koji Mizutani, Taichen Lin, and Takanori Iwata

                  pp. 2479 - 2482

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A scientometric study on Wnt and Notch signaling pathways in oral potentially malignant disorders and oral cancer
Xiaoliang Luo, Yiwen Deng, and Hao Wu

                  pp. 2483 - 2488

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A scientometric study on research trends and characteristics of halitosis
Xiaole Liu, Ye Zhang, Qingqing Liu, Chengsu Hou, and Ling Xu

                  pp. 2467 - 2471

Correspondences

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Long-term stability of maxillary anterior tooth-implant supported fixed prostheses: A 14-year case report
Yuan-Yang Hsu, Shyh-Yuan Lee, Cheng-Shan Li, Chun-Yu Wang, and Shing-Zeng Dung

                  pp. 2544 - 2546

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Limitations of bibliometric analysis: Evidences from trigeminocardiac reflex published in Journal of Dental Sciences
Li-Chiu Yang, Michelle Chao, and Yu-Chao Chang

                  pp. 2559 - 2560

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A novel surgical approach for benign deep lobe of parotid gland tumors: Utilizing the Santorini fissure
Hao Lu, Shengwen Liu, Wanlin Xu, and Wenjun Yang

                  pp. 2556 - 2558

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Managing an extensive, complicated crown fracture through direct fragment reattachment
Saeed Asgary

                  pp. 2564 - 2566

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Long-term stability of maxillary molar intrusion using temporary anchorage devices: A 17-year case report
Ting-Hsin Huang, Cheng-Shan Li, Yi-Hung Chen, and Shing-Zeng Dung

                  pp. 2561 - 2563

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Vital pulp therapy of a complicated crown fracture in a child
Saeed Asgary

                  pp. 2553 - 2555

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A Japanese dentist immigrant described by the writer, Chihei Nakamura, during the Japanese colonial period
Feng-Chou Cheng, Ling-Hsia Wang, Wen-Hsun Chang, and Chun-Pin Chiang

                  pp. 2547 - 2549

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The story of a radiation technician covering dental radiology in Taiwan during the Japanese colonial period - Mr. Sakae Kawahara (1904–1943)
Feng-Chou Cheng, Ling-Hsia Wang, Yu-Ting Hu, and Chun-Pin Chiang

                  pp. 2550 - 2552

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Treatment of temporomandibular joint disorder with traditional Chinese medicine under the national health insurance system in Taiwan
Feng-Chou Cheng, Ling-Hsia Wang, Wen-Chiung Chang, and Chun-Pin Chiang

                  pp. 2541 - 2543

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Exploring the framework of professional subspecialties for dental technicians
Ching-Shuen Wang, Feng-Chou Cheng, Wei-Chun Lin, and Chun-Pin Chiang

                  pp. 2538 - 2540

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Digital workflow for full-arch immediate loading: Dynamic navigation and 3D printing fixed dental prostheses
Cheng-Chung Lin, Han-Wei Lin, Yu-Chieh Lin, and Wei-Chun Lin

                  pp. 2536 - 2537

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The tongue piercing fashion and its related health costs: A perspective of clinical dentistry in Taiwan
Feng-Chou Cheng, Ling-Hsia Wang, Julia Yu-Fong Chang, and Chun-Pin Chiang

                  pp. 2533 - 2535

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Surgical management of maxillary incisor with palatal radicular groove and endodontic-periodontal lesion
Le Lu, Ya Shen, and He Liu

                  pp. 2527 - 2529

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Differential diagnosis of a painful swelling lesion in the facial region: A case report of Merkel cell carcinoma
Yan-Zhi Wang, Pei-Hui Chen, Yang-Che Wu, and Chih-Yuan Fang

                  pp. 2524 - 2526

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Dynamic navigation technology combined with zygomatic implants as a surgical strategy for insufficient maxillary bone volume
Han-Wei Lin, Cheng-Chung Lin, Wei-Shao Lin, and Wei-Chun Lin

                  pp. 2518 - 2520

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Bio-obturation in traumatized mandibular teeth: A complex case report
Saeed Asgary

                  pp. 2521 - 2523

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Postoperative carotid sinus syndrome presenting as sinus pause in an oral cancer patient: A rare but clinically significant case
Tzu-Hao Hsiao, Tung-Nien Hsu, and Po Chih Hsu

                  pp. 2506 - 2507

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Endodontic treatment and anxiety: Exploring cortisol-driven stress mechanisms
Wesley Viana, Silmara Silva, Christianne Velozo, and Diana Albuquerque

                  pp. 2513 - 2514

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Simultaneous presentation of three types of osteoid osteoma in the maxilla
Jen-Ho Wen, Chen-Yu Heieh, Yang-Che Wu, and Chih-Yuan Fang

                  pp. 2515 - 2517

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Application model of reading the medical images from the National Health Insurance (NHI) MediCloud System for clinic dentists: A case report
Feng-Chou Cheng, Chia-Hua Shih, Yu-Jie Shen, and Chun-Pin Chiang

                  pp. 2508 - 2510

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Surgical removal of an asymptomatic radicular cyst after 10 years of follow-up
Feng-Chou Cheng, Ching-En Meng, Pei-Yu Hsu, and Chun-Pin Chiang

                  pp. 2503 - 2505

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Current challenges of the implementation of radiology diagnosis equipment operating license for the dentists in Taiwan
Feng-Chou Cheng, Yan-De Liou, Bo-Lin Liu, and Chun-Pin Chiang

                  pp. 2511 - 2512

Case Report

Short Reviews

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Sugar-sweetened beverages and oral health in Taiwan: An emerging public health challenge
Yu-Chao Chang, Hui-Chieh Yu, and Tsung-Po Chen

                  pp. 2492 - 2493

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Career choices in graduates from the Taipei Third Girls high school in 1936 – With special emphasis on those hoping to study dentistry
Feng-Chou Cheng, Ling-Hsia Wang, and Chun-Pin Chiang

                  pp. 2494 - 2496

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Perspectives of the new horizon in bone regeneration with standardized, centrally manufactured freeze-dried platelet-rich plasma
Yu-Chao Chang, Yi-Tzu Chen, and Pei-Yin Chen

                  pp. 2489 - 2491

Cover art