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DOI

10.1016/j.jds.2025.03.004

First Page

1899

Last Page

1903

Abstract

Abstract Background/purpose Salivary adenoid cystic carcinoma (SACC) affects the major salivary glands and minor salivary glands mainly within the oral cavity. The purpose of this study was to analyze the scientometric characteristics and research trends of SACC. Materials and methods All the papers on SACC were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and 2015–2024 in the analysis of research trends. Results There were 2406 papers on SACC, with total citations of 54,921 and the h index of 97. Cancer surgery, radiotherapy, chemotherapy, cisplatin, doxorubicin, neck dissection, and combined modality therapy were the main keywords of treatment. The trend of clinical study on cell differentiation, doxorubicin, and fluorouracil has changed to clinical trial, cohort analysis, diagnostic imaging, positron emission tomography-computed tomography (PET-CT), intensity modulated radiation therapy, neck dissection, and surgical margin after 2015. The trend of laboratory investigation on cancer cell culture, cytology, protein S100, and flow cytometry has changed to epithelial mesenchymal transition, fluorescence in situ hybridization, gene fusion, microRNA, MYB, protein Myb, protein p63, and signal transduction after 2015. Conclusion This study for the first time elucidated the current scenario and scientometric characteristics of SACC, and would help in improving in reciprocal collaboration and provide helpful guidance for further research.

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