DOI
10.1016/j.jds.2012.09.026
First Page
285
Last Page
288
Abstract
Abstract Peculiar findings of orofacial actinomycosis mimicking the clinical appearance of a tumor of the upper gingiva are reported. An 83-year-old man with bleeding of the gingiva visited our hospital. The clinical diagnosis was a benign gingival tumor, and the lesion was surgically removed. Histologically, the excised specimens showed an ulcerative granuloma lesion covered by bacterial colonies consisting of club-shaped filaments. DNA samples were extracted from paraffin sections and examined by polymerase chain reaction (PCR) for Actinomyces species. The PCR products examined by direct DNA sequencing demonstrated the presence of Actinomyces israelii . Finally, a pathological diagnosis was made of a pyogenic granuloma associated with actinomycosis. The PCR method aided the early and exact diagnosis of the paraffin-embedded sample of oral mucosal infectious diseases including actinomycosis.
Recommended Citation
Kuyama, Kayo; Fukui, Kenji; Ochiai, Eriko; Wakami, Masanobu; Oomine, Hirotaka; Sun, Yan; Morikawa, Miyuki; Iwadate, Kimiharu; and Yamamoto, Hirotsugu
(2018)
"Pyogenic granuloma associated with Actinomyces israelii,"
Journal of Dental Sciences: Vol. 13:
Iss.
3, Article 1.
DOI: 10.1016/j.jds.2012.09.026
Available at:
https://jds.ads.org.tw/journal/vol13/iss3/1